1964-	Singapore Cancer Society was formed by individuals from the Rotary Club of Singapore, the Lions Club and the Jaycees.
1965-	Society was officially registered with the Registry of Societies. The first education campaign, "The Eight Warning Signs of Cancer", was launched.
1966-	Society was admitted to the global cancer organization, International Union Against Cancer (UICC). His excellency, Inche Yusof Bin Ishak, then president of Singapore, gave consent to be the first patron.
1967-	Temporary office premise was set up at Cancer Information Centre, Singapore General Hospital, Welfare Committee was formed.
1969-	The PAP Smear Screening Clinic was opened.
1973-	The Research to Recovery Programme, a rehabilitation and support group for mastectomies was established. The Cancer Research Fund was launched.
1975-	Society moved to Peace Centre and hosted the 2nd Asia Pacific Cancer Conference.
1976-	The Stoma Rehabilitation Committee was formed.
1979-	The Smoking Cessation Clinics were launched.
1980-	Society moved to new premise at Realty Centre.
1984-	The Helping Hands Committee was firmed and the New Voice Club for laryngectomees and Listener's Group, a phone-counseling service fell under its purview.
1987-	The Hospice Group was launched.
1993-	Society became the beneficiary of the annual Terry Fox Run, a fund-raising project for Cancer Research.
1994-	Society took over the management of the Jonathan Tan Fund, a fund disbursed to leukemia children.
1998-	Society organized the UICC Workshop on "Nasopharyngeal Cancer"
1999-	Organized the conference on "Threats of Tobacco on Children & Youth".
2000-	Hosted the 13th Biennial Congress of the World council of Enterostomal Therapists (WCET) : Theme - Enterostomal Therapy - Onto the 21st Century. Organized the "Relay For Life".
2001-	Hosted the 3rd UICC Cancer Management Meeting : Theme- Quality Cancer Care in the New Millennium.
2002-	Launched the 1st Colorectal Cancer Awareness Month in March -Opening of CAncer Screening & Education Centre @ Boon Keng.
2004-	The Society marked its 40th anniversary with its inaugural The Cancer Charity Show to raise funds for the cancer cause as well as to promote cancer awareness within the community.
2005-	The Singapore Cancer Society Fund was launched in April to help needy cancer patients with their treatment costs. A Singapore Cancer Society Centre was also set up at the National Cancer Centre for the convenience of the patients to apply for assistance through this Fund.