My Happy, Healthy Family | Cancer & Family History: Prostate Cancer
   
 
 
 
 
 
   
 
   
 
 
 
 
 
 
 
 
 
   
 
   
 
   
 
   
 
   
 
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
 
   
Prostate Cancer

 

What Is The Prostate Gland?
The prostate gland is a walnut-sized gland situated below the urinary bladder. It is enclosed by a capsule. It produces prostatic secretion which forms part of semen.

What Is Prostate Cancer?
Prostate cancer develops when cells in the prostate gland turn malignant i.e. uncontrolled growth, and forms a lump. This cancer grows out of the prostate capsule and invades surrounding tissue e.g. seminal vesicles, bladder neck. It can also spread to lymph glands in the pelvis. It also often spreads via the blood stream to the backbone.

Studies have shown that many middle-aged men (above 50 years) harbour small prostate cancers which do not cause any symptoms and are clinically insignificant.

How Common Is Prostate Cancer?
Prostate cancer is the most common cancer in American men. In Singapore, it is the 6th most common cancer in men. About 150 new patients are diagnosed every year in Singapore. With the incidence rate increasing at 5% yearly, more Singapore men will be affected.

Risk Factors
At present, not much is known about the risk factors but the following have been identified:

Family history (father, brother, uncle) of prostate cancer
Age. 96% of patients are above 55 years old
Race. Risk is higher for black Americans, Scandinavians but low in Asians
Diet rich in animal fat
Previous vasectomy

Sexual activity is not a risk factor.

Screening for Prostate Cancer
Prostate cancer can be detected at an early stage by:

a) Digital Rectal Examination (DRE)
b) Blood level of Prostate-Specific Antigen (PSA). PSA of more than 4 mg/ml is abnormal

It is recommended that men above 50 years old to have a DRE and PSA test every year. Please consult a doctor for these tests.

Signs & Symptoms

1. Lump in the prostate gland that is often asymptomatic. This lump is detected during a Digital Rectal Examination (DRE) performed by a doctor. The cancer can also be detected by an elevation of PSA in the blood. PSA stands for Prostate-Specific Antigen and is a tumour marker.
2. Difficulty in passing urine due to obstruction to the passage of urine.
3. Back pain due to the spread of cancer to the bone (metastases).
4. Weakness or swelling of lower limbs due to cancer obstruction of the lymphatic channels.

2, 3 and 4 are symptoms of advanced prostate cancer.

No signs are specific for prostate cancer. It is safer to see a doctor first to exclude other causes of symptoms such as urinary tract infection, benign prostate hyperplasia, urinary stones, etc.

 
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